"The problems of disease are more complicated and difficult than any others with which the trained mind has to grapple... Variability is the law of life. As no two faces are the same, so no two bodies are alike, and no two individuals react alike and behave alike under the abnormal conditions which we know as disease. This is the fundamental difficulty in the education of the physician, and one which he or she may never grasp... probability is the guide of life".Here lies the basis for clinical decision making and evidence based medicine. What is the probability that "Liver extract" will improve fatigue or that Astaxanthin (a carotenoid pigment) will solve male infertility? (more of these later)
Sir William Osler 1, 1921
For that matter, what is the probability that any given clinical trial sponsored and controlled by GlaxoSmithKline, Merck, or Procter and Gamble will be honest?
This quote appears on a few websites promoting magical medicine. However they routinely omit the last sentence of the quotation, reversing the essence of Osler's wisdom. Osler would not have liked magical medicine - of the "GlaxoSmithKline" variety or the "liver extract" variety.
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Labels: Osler Corner